What is ProgenMix™ and how is it used?

ProgenMix™ is RMS’s proprietary pancreatic differentiation media formulation, designed to support the efficient and reproducible generation of PDX1+ pancreatic progenitor cells and endocrine cell types from induced pluripotent stem cells. It is intended for researchers and biotech companies that wish to generate pancreatic cells in-house, rather than purchasing ready-to-use cells through the ILC Cell Kit.

PDX1 (Pancreatic and Duodenal Homeobox 1) is a key transcription factor in pancreatic development and a critical marker of pancreatic progenitor cells. The ability to reliably generate PDX1+ progenitor cells is an important step in the differentiation of iPSCs toward functional beta-like cells. ProgenMix™ provides a validated, optimized media formulation that supports this step with consistency and reproducibility.

ProgenMix™ is designed for use in research settings including diabetes research, developmental biology, and the development of iPSC-based cell models for drug discovery. It reflects the same scientific rigor that underlies RMS’s therapeutic program and is backed by the company’s extensive experience in pancreatic cell differentiation. Researchers using ProgenMix™ benefit from protocols that have been refined through years of hands-on work at the interface of academic stem cell science and translational biotechnology.

Learn more about ProgenMix™.